In POE Ultimate Apothecary Farming Guide, we go over the best farming strategies for the Apothecary card in the Path of Exile 3.20 league!
Best Strategies To Farm Apothecary & Divine Cards in POE 3.20 | Path of Exile Apothecary Farming Guide
Here we give you a brief overview of each farming strategy, covering the atlas tree setup, items to use, and cost:
POE 3.20 Apothecary Best Farming Method 1
This is the best way to farm a Mageblood with Apothecary Cards. Able to farm up to 10 Divines Profit an Hour. Being one of the most lucrative Farming Strategies for 3.20 Forbidden Sanctum. With this strategy, we're going to utilize strong boxes in Abyss to farm divination cards, the main source obviously is the strong boxes, and the secondary source we're going to be the Abyss, which is absolutely busted this league just giving so many enemies, it's good for filling with the Delirium bars it's good for getting divination cards and layouts, so that means those can drop scarabs and fractured items.
And also you can round up the strategy with Breach or Harbinger, based on the map if you're running Crimson Temple having is going to be better but if you're running the fire cast usually your build needs a bit more space. The breach is going to be good in case you use Caustic Arrow, but if you build something like Spark or kinetic blast, Crimson temple with Harbinger is going to feel better. And we're going to round up the strategy with Delirium you can either add 20% or 40% Delirium Orb if you bolt. It isn't that strong yet you run too much of it and just use fine Delirium orbs and get some darker half or divide orbs from it. Or you can use Skittering delirium orbs and fully sustain all the scallops that you need by using a 6% delirium scatter ranked with Skittering orbs.
Core Strategies & Maps
Main Sources
Strongbox: Main Source Divination Cards
Abyss: Secondary Source Divination Cards, Deli Bar Filler
Breach / Harbinger: Filler
Delirium: 20-40% Fine Delirium Orb, 60+% Skittering Delirium Orb
Alternative Maps
Method Setup:
Sextants: 2 Additional Strongbox, Enraged Strongbox Monsters, Additional Abyss
Scarbs: Gilded Ambush Scarab, Gilded Blight Scarab, Gilded Divination Scarab
Breach: Additional Breach
Harbinger: Boos is Guarded by a Harbinger
MF (Gear) Setup: 9-10% Rings, 15% Body, 10% Gloves, 20% Boots, 5% Belt, 68-70% Quant
Altas Tree:
Cost:
T16 Crimson Temple: 5c x 48
additional Abyss Sextant: 5c x 12
Enraged Strongbox Sextant: 50c x 12
additional Strongbox: 7c x 12
elevated additional Breach: 120c x 3
Gilded Breach: 5c x 48
Gilded Divination: 12c x 48
Gilded Abyss: 6c x 48
Gilded Ambush: 11c x 48
Delirium Orb: 10c x 48
Breach Map Device: 4c x 48
Total: 3,648c (par map 76c)
Scarabs & Delirium Orb can be sustaned by suing 60+% with Skittering Orbs
Result:
Total Profit: 18.737c
in Divines: 81,46521739
Profit per Map: 390,35
Time per Map: 10Min
Maps per Hour: 6 Maps
Profit Per Hour: 2.342c
in Divines: 10,18
POE 3.20 Apothecary Best Farming Strategy 2
This is a strong box farming strategy, but each map takes around 4 to 5 minutes depending on how lucky you are. Right now, this method is super RNG due to the wide variance in Apothecary Drops. Strongbox Compasses are extremely expensive as it is the only way to get monsters to drop rare loot after the global nerf to Qualntity/Rarity on past league mechanics. Even with the high cost of mats, you can still maintain a slight profit if you go unlucky on Apothecary Drops as long as you have another profitable mechanic built into your farming strategy!
Farming Method:
Scarabs: Winged Reliquary, Winged Cartography, Winged Divination, and Winged Ambush
Compass: 600% Enraged Strongbox, +3 Additional Strongbox, 20 Quality, and 8 Mod Corrupted Maps
Atlas: Wandering Path for Maximum Quantity with Focus on Map Drops/Duplication
Map Device: Delirium
Altas Tree:
Costs:
Winged Scarabs cost around 7 per 1 Divine
Scarab Cost for 1 Map: 140c
Compasses: 20 Quality - 50C, Enraged Strongbox - 180C, 8 Mod Maps - 105c, Additional Strongbox - 2 Divines for 16 Use
Compass Cost for 1 Map: 104c
Map Device Cost: 10c
Cost of 8 Mod Map: 10c
Total Cost per Map: 264c
Each Map costs around 1 Divine to run
Results:
Ended up running 57 maps total for a total cost of around 60 Divines
Total Exilence Amount: 70 Divines
Seven Years Bad Luck: 4, Enlightened: 7, Dragon's Heart: 3
0 Apothecaries
Each map takes around 4 to 5 minutes to finish, so running 60 maps would take around 5 hours with 100% efficient play
Total Profit: 2 Divines / Hour
PoE 3.20 Low Budget Apothecary Farming Strategy
Then if you lack in budget, here we share with you the cheaper MF strategy for farming Apothecary card
Atlas Tree:
Items Requroied and Cost:
Enraged: 18c per map
Corrupted Strongbox: 1.75c per map
Magic Pack Size: 1.25c per map
Crimson Temple Guardian Map: 30
Glided Divination: 12
Rusted Elder: 1
Glided Ambush: 10
Glided Reliquary: 4
Beyond on Map Devic: 5
Cheapest Delirium Orb: 4
Total: 88.25 per map
More Tips for Farming Apothecary & High-End Divine Cards In POE
Impact of Apothecary Drop
Apothecary (Value: 58 Divines) Drop rate is probably around 1 in 60 to 80 maps. With an Apothecary drop, the Divine/Hr Ratio is somewhere around 10 to 12 Divines/Hr, which makes it one of the best money-making methods in the game. This was done with Magic Finding and Quantity, so if you do it without MF, then your results will be considerably worse.
How To Be More Profitable When You Farm Apothecary Cards?
All Apothecary Farming methods revolve around finding ways to generate consistent profit to sustain yourselves until the lottery drop.
Corrupted 8 mod maps, Harbinger (Fracturing/Mirror Shard), Delirum Orbs (Skittering/Diviner's), Infinite Harvest/Winged Scarab Enchant
Using Winged Reliquary Scarabs over Gilded will most likely result in a loss unless you get lucky with a high-value Unique
Increasing Clear Speed and efficiency is the most important factor in being more profitable, buy your mats in bulk.
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