Borderlands 4 Best Bosses & Spots To Farm (Early & Endgame)

Are you searching for the most efficient ways to rack up legendaries, powerful gear, and experience in Borderlands 4? Here we are going to sort out the best bosses and farming spots in BL4, both for farming in the early game and pushing through the endgame. From solo-friendly routes to co-op exploits, here’s everything you need to know to maximize loot and XP while tackling the best bosses in the game.

Top 10 BL4 Best Bosses & Spots To Farm (Early & Endgame)

Farming in Borderlands 4 revolves around defeating specific bosses or clearing enemy waves in certain areas, then resetting the encounter for repeated loot drops. Most spots feature a Moxxi’s Machine (or a similar boss reset mechanism) and safe fast-travel points nearby. Many bosses have unique loot pools with exclusive legendaries, and certain exploits can dramatically speed up your farming runs.

Some locations are best suited to solo runs, offering quick resets and manageable enemies, while others shine in co-op for those wanting to maximize efficiency or share loot. Some farms focus on XP, others are tailored for legendary drops, and a few strike a balance between both.

Below, we are going to sort out the best bosses and locations to farm and how to set up to max your legendaries, loot, and XP effectively:

1. Splash Zone (Riptide Grotto)

Recommended for: Early & endgame, solo or co-op

Splash Zone stands out as a classic boss farm for both early progression and late-game loot. The boss is easy to defeat, and you can reset and run the fight in rapid succession. This spot is well-known for dropping one of the best shields in the game, a solid shotgun, and several strong grenade mods, no matter your level.

• Tips (How To Farm): For solo, simply reset and fight repeatedly. In multiplayer, one player can work the reset while the other jumps in and out of the arena, resulting in almost instant boss respawns.

• Reset Method: Use Moxxi’s Machine by the arena for a fast respawn.

• Loot (What To Farm): Frequent legendaries, including shields, shotguns, and grenades.

2. Pitted Stain (Idolator's Noose)

Recommended for: Early game

Located in the south of the map, the Pitted Stain is accessible as soon as you reach the main hub. It’s a ripper drill site with three bosses: Frank the Furnace, S the Engineer, and Hank the Welder, giving you three shots at legendaries every run. The site has easy difficulty, but the drop rates are just as good as later-game farms.

• Tips (How To Farm): Wipe out the waves, then take on the trio of bosses. Bring fire weapons; all three are weak to that element. Grappling to a high vantage point lets you snipe safely.

• Reset Method: Either fast travel out and back in, or simply use the Moxxi sign at the gate for a 30,000 credit respawn.

• Loot (What To Farm): Multiple chances at legendaries and a reliable source of early upgrades.

3. Sor's Clench Drill Site (Ruined Sumplands)

Recommended for: Early & mid-game, solo or co-op

Sor’s Clench offers a trio of bosses, each with a different elemental weakness: fire, frost, or corrosive. This site delivers excellent loot opportunities and is even better thanks to a nearby ammo vendor, so you can keep going without stopping.

• Reset Method: Use Moxxi’s Machine outside the gate for quick resets.

• Tips (How To Farm): Cycle through weapons matching the elemental weaknesses for fast clears.

• Loot (What To Farm): High chance at legendaries from three unique bosses.
  

4. Queen's Cradle (Tonnage Peel)

Recommended for: Early-mid game (after mission 9), solo or co-op

After finishing the “Unpaid Tab” story mission, you’ll access Queen’s Cradle in the northwest. The boss in the Ripper Room drops a ton of legendaries and the fight is straightforward, letting you focus on farming loot rather than crowd control. Many players report higher legendary rates here than anywhere else.

• Reset Method: Leave through the doors, grapple into the purple portal, and use Moxxi’s sign to respawn the boss.

• Tips (How To Farm): This spot is efficient for both solo and co-op, and seems to have above-average legendary drop rates. Focus on the boss, then run through the portal to restart the fight quickly.

• Loot (What To Farm): Consistent legendaries and valuable gear.
  

5. Sludgemore (Idol’s Noose)

Recommended for: Early & mid-game, solo or co-op

This miniboss farm is quick to set up after two short side quests: “Null and Void” and “All Charged Up.” Sludgemore is a worm-like boss that surfaces for close combat, but can be safely managed with ranged attacks and cover. The loot pool includes the Kickballer rocket launcher and Onion Shield, great for explosive builds.

• Reset Method: Use the nearby Moxxi sign or have a teammate ready to reset while you remain in the boss arena.

• Tips (How To Farm): Stay mobile and use terrain for cover. A partner can reset the fight instantly by standing at the Moxxi sign.
  Reset Method: Moxxi sign at the entrance for fast respawn.
  

• Loot (What To Farm): Unique weapons such as the Kickballer, plus shields like the Onion Shield which pairs perfectly for explosive builds.

6. Foundry Freaks Drill Site (Someday Rise)

Recommended for: XP & loot (early & mid-game), solo or co-op

Known for its generous waves of enemies and a trio of bosses at the end, Foundry Freaks is a hotspot for leveling up and farming loot. Builds with strong area damage can clear the entire arena in about a minute.

• Reset Method: Use Moxxi’s Machine after each run.

• Tips (How To Farm): Bring weapons with area damage for mobbing, and don’t be afraid to lower the difficulty for speed runs. Use area-of-effect weapons for mobbing, and save your super for the bosses.

• Loot (What To Farm): High XP from waves, exclusive legendaries from bosses.
  

7. Battle Wagon Drill Site (Snowy Wells)

Recommended for: Mid-game, solo or co-op

Battle Wagon is a boss with multiple enemies attached, and defeating them all nets a pile of loot. Lowering his health in stages causes more enemies to spawn for extra drops.

• Reset Method: Moxxi’s Machine at the site for quick reset.

• Tips (How To Farm): Avoid killing the boss instantly, take its health down gradually to spawn more loot-dropping enemies.
  

• Loot (What To Farm): Tons of purples and legendaries, especially from the boss’s attachments.

8. Double Drill Site Boss Loop (Sor's Clench & Old Scrape)

Recommended for: Endgame loot & XP, solo or co-op

For those at endgame, the most efficient farm involves cycling between two drill sites: Sor’s Clench and Old Scrape. With five bosses between them, you can defeat all, skip waves, and jump back and forth for almost non-stop legendary drops and XP.

• Reset Method: Initial reset at each site, then alternate between them without further resets.

• Tips (How To Farm): Sometimes not all bosses spawn, but over multiple cycles you consistently get five bosses per loop. Loot and XP are excellent, and runs are incredibly fast, especially if you ignore non-boss enemies. Only reset each drill site once at the start. After that, never use Moxxi’s Machine, just fast travel between the two and clear the bosses each time.

• Loot (What To Farm): Five boss loot drops per full loop - legendaries, XP, and even overloot.

9. Horus & Sydney Pointy Leg (Driller Area)

Recommended for: Early & mid-game loot, solo or co-op

Both are located close together, making it easy to alternate between them. The Horus boss is a flyer and drops great loot, including a red chest. Sydney Pointy Leg is loaded with bandits and psychos for fast XP and loot.

• Tips (How To Farm): Bring shock and fire weapons for Horus. Use area damage for Sydney Pointy Leg.

• Reset Method: Moxxi’s Machine and/or fast travel for resets.

• Loot (What To Farm): Multiple legendaries, red chest loot, fast XP.

10. Axemore (Toil of Spoiling Abandoned Mine)

Recommended for: Endgame legendary farming, solo or co-op

Axemore is an abandoned mine boss available after the main campaign. He drops the Bud, an all-rounder weapon that counts as every gun type for challenges, plus the Killspring Blood Siphon and the Buzz Axe. The fight itself is straightforward, and the location is accessible from the Final Defiance fast travel station.

• Tips (How To Farm): Ignore most enemies on the way, drop down to the boss room, and focus fire.

• Reset Method: Use the Moxxi reset machine or simply run the mine again.

• Loot (What To Farm): The Bud weapon, Killspring Blood Siphon, Buzz Axe, and other mine-specific legendaries.

11. Driller Hole (Lowrise)

Recommended for: Solo or co-op, weapon farming

At Driller Hole, you can quickly reach the boss for a chance at Katagawa’s Revenge (a top-tier sniper) and several other snipers and pistols. This spot stands out for its speed, you can take the portal, drop in, and reset almost instantly, making it one of the fastest weapon farms.

• Tips (How To Farm): Skip most enemies, head straight for the boss, and use the nearby ammo dump if needed.

• Reset Method: Return to the entrance and use the portal, or restart the area by running back up.

• Loot (What To Farm): Katagawa’s Revenge and three other sniper rifles; random pistols.

12. Red Chest Farm (Still Shore / Abandoned Post)

Recommended for: Early game, solo

A quick way to grab gear early in your playthrough, this farm involves defeating a badass enemy near a chained red chest. Once the chest is open, you can quit out and reload for another try.

• Tips (How To Farm): Eliminate the required badass, open the chest, save and quit, then reload your game for another roll.

• Reset Method: Save and quit, then reload to respawn the chest.

• Loot (What To Farm): Legendaries and high-rarity gear, though RNG can be harsh.

13. Callus Harbinger of Annihilating Death (Heritage Opus)

Recommended for: Mid-game, solo or co-op

This large boss is an easy target for shock and corrosive weapons. The fight is simple, and you get a chest after each kill. The Hot Slugger, one of the best weapons for boosting your damage, drops here.

• Tips (How To Farm): Aim for the critical spot and bring strong elemental weapons for quick clears.

• Reset Method: Use the portal at the back of the arena to reset, or return via the entrance.

• Loot (What To Farm): The Hot Slugger and other powerful gear, plus a bonus chest.

14. Leader Willm (Sidequest Chain Boss)

Recommended for: Co-op, endgame

Leader Willm becomes farmable after finishing a chain of five sidequests. This boss can be reset incredibly fast in co-op by having one player stand at Moxxi’s machine while another triggers the fight.

• Tips (How To Farm): One player jumps down to the boss, the other resets; use ranged weapons for quick kills.

• Reset Method: Moxxi’s Machine for instant respawn (co-op optimized).

• Loot (What To Farm): Strong class mods and a variety of legendaries.

15. Core Observer (Black Lime Bunker)

Recommended for: Co-op, mid to endgame

Once the Black Lime Bunker is available (after story progression), Core Observer can be farmed using the reset trick: one player at the machine, one at the boss.

• Tips (How To Farm): Stand near the portal exit; coordinate with your co-op partner for near-instant boss resets.

• Reset Method: Moxxi’s Machine.

• Loot (What To Farm): Various legendaries and unique loot tied to the bunker.

16. Fractice (Cruel Craft Order Bunker)

Recommended for: Co-op, endgame, advanced players

Farming Fractice requires special positioning, jumping to a tricky ledge using the Noisy Cricket weapon for rocket-jumping. Once in place, you can repeatedly spawn and defeat the boss while your partner resets.

• Tips (How To Farm): Use high-shield builds and coordinate jumps; practice the movement to reach the right ledge.

• Reset Method: Moxxi’s Machine, triggered by your co-op partner.

• Loot (What To Farm): High-end loot and class mods.

17. Vault Bosses: Primordial Garden of Erratics & Regal (Carcalia Burn/Terminus Range)

Recommended for: Co-op, endgame

Both of these vault bosses are best tackled in co-op, using precise spots in the boss arena to allow for rapid resets. They offer amazing class mods and exclusive loot.

• Tips (How To Farm): Mark the reset spot on the floor with dropped items for consistency; have one player at the reset machine, the other in the arena.

• Reset Method: Moxxi’s Machine.

• Loot (What To Farm): High-tier class mods and unique vault loot.

18. Double Drill Site XP Farm (Sydney Pointy Legs & Foundry Freaks)

Recommended for: Co-op, XP and loot

By splitting your team between these two nearby drill sites, you can double up on XP and loot without dragging players across the map. Both are packed with enemies and bosses, yielding strong rewards for both experience and gear.

• Tips (How To Farm): Have half the team at each drill site; coordinate resets and clear waves rapidly.

• Reset Method: Moxxi’s Machine at each drill site.

• Loot (What To Farm): High XP, plenty of legendaries from bosses and mob waves.